Question 1

Which immunoglobulins play a part in allergic reactions such as asthma?

Accepted Answer

A)   IgA
B)   IgD
C)   IgE
D)   IgME) None of the above
F) A) and B)

Question 2

In a protein antigen, how many amino acids are necessary for the antigen to bind to a receptor on a T cell?

Accepted Answer

A)   1 or 2
B)   3 to 5
C)   5 to 7
D)   10 to 15E) A) and B)
F) A) and C)

Question 3

The monoclonal antibody drug Trastuzumab is used in the treatment of which disease?

Accepted Answer

A)   breast cancer
B)   prostate cancer
C)   non-Hodgkin's lymphoma
D)   none of theseE) B) and D)
F) B) and C)

Question 4

The HIV genome is which of the following?

Accepted Answer

A)   a single stranded DNA
B)   a double stranded DNA
C)   a single stranded RNA
D)   a double stranded RNAE) All of the above
F) B) and C)

Question 5

Which of the following is true?

Accepted Answer

A)   Both embryonic and adult stem cells are usually pluripotent.
B)   Both embryonic and adult stem cells are usually multipotent.
C)   Embryonic stem cells are usually pluripotent, but adult stem cells are usually multipotent.
D)   Embryonic stem cells are usually multipotent, but adult stem cells are usually pluripotent.E) A) and C)
F) A) and B)

Question 6

Plasma cells are derived from which type of cells?

Accepted Answer

A)   B cells
B)   helper T cells
C)   macrophages
D)   memory T cellsE) A) and D)
F) B) and D)

Question 7

Interferon is associated with the function of which of the following?

Accepted Answer

A)   B cells
B)   macrophages
C)   NK cells
D)   T cellsE) B) and D)
F) A) and B)

Question 8

In HIV the protease and reverse transcriptase are enclosed by which of the following?

Accepted Answer

A)   the p17 matrix
B)   the p24 capsid
C)   gp41
D)   gp120E) B) and D)
F) B) and C)

Question 9

Which of the following cells have both activating and inhibitory receptors?

Accepted Answer

A)   B cells
B)   macrophages
C)   T cells
D)   all of theseE) A) and D)
F) None of the above

Question 10

Which of the following binds to residues on gp120 which cannot mutate very much?

Accepted Answer

A)   b12
B)   2G12
C)   p7
D)   p17E) B) and D)
F) None of the above

Question 11

If the following image depicts a virus in a weakened state,  which of the choices would represent the type of vaccine that might be the safest to use?

Accepted Answer

A)   
B)   
C)   
D)   All would have the same degree of risk.E) A) and B)
F) A) and C)

Question 12

How many polypeptide chains does a T-cell receptor have?

Accepted Answer

A)   1
B)   2
C)   3
D)   4E) None of the above
F) C) and D)

Question 13

Which of the following bests describes the effort to find a vaccine against HIV?

Accepted Answer

A)   Since the virus is known to mutate rapidly there is no interest in developing a vaccine.
B)   There has been considerable research activity, but no clinical trials have been conducted.
C)   The clinical trials have been failures.
D)   A promising vaccine is currently available.E) B) and C)
F) A) and D)

Question 14

Which portion of a T-cell receptor is furthest from the cell membrane of the T cell?

Accepted Answer

A)   the amino end of the constant domain
B)   the amino end of the variable domain
C)   the carboxylate end of the constant domain
D)   the carboxylate end of the variable domainE) A) and D)
F) A) and C)

Question 15

Which of the following will be recognized as foreign by the activating receptors of macrophages?

Accepted Answer

A)   lipopolysaccharides of gram-negative bacteria
B)   peptidoglycans of gram-positive bacteria
C)   both a and b
D)   neither a nor bE) All of the above
F) A) and B)

Question 16

Which of the following is not a side effect of glucocorticoids?

Accepted Answer

A)   diabetes
B)   osteoporosis
C)   skin atrophy
D)   None, these are all side effects of glucocorticoids.E) B) and D)
F) C) and D)

Question 17

V(J) D recombination is associated with which of the following?

Accepted Answer

A)   B cells
B)   macrophages
C)   T cells
D)   all of theseE) A) and B)
F) All of the above

Question 18

Which level of protein structure is most useful in classifying cytokines?

Accepted Answer

A)   primary
B)   secondary
C)   tertiary
D)   quaternaryE) B) and D)
F) A) and B)

Question 19

Plasma cells do which of the following?

Accepted Answer

A)   directly attack the antigen
B)   secrete additional antibodies
C)   both a and b
D)   neither a nor bE) A) and B)
F) A) and C)

Question 20

If the following image depicts a virus in a weakened state,  which of the choices would represent an inactivated vaccine?

Accepted Answer

A)   
B)   
C)   
D)   Any of these could represent an inactivated vaccine.E) None of the above
F) A) and C)

Exam 31: Immunochemistry

The HIV genome is which of the following?

Correct AnswerverifiedShow Answer

V(J) D recombination is associated with which of the following?

Correct AnswerverifiedShow Answer

The monoclonal antibody drug Trastuzumab is used in the treatment of which disease?

Correct AnswerverifiedShow Answer

How many polypeptide chains does a T-cell receptor have?

Correct AnswerverifiedShow Answer

Which level of protein structure is most useful in classifying cytokines?

Correct AnswerverifiedShow Answer

If the following image depicts a virus in a weakened state, which of the choices would represent an inactivated vaccine?

Correct AnswerverifiedShow Answer

Which of the following is not a side effect of glucocorticoids?

Correct AnswerverifiedShow Answer

Plasma cells do which of the following?

Correct AnswerverifiedShow Answer

Interferon is associated with the function of which of the following?

Correct AnswerverifiedShow Answer

Which immunoglobulins play a part in allergic reactions such as asthma?

Correct AnswerverifiedShow Answer

Which of the following is true?

Correct AnswerverifiedShow Answer

Which of the following binds to residues on gp120 which cannot mutate very much?

Correct AnswerverifiedShow Answer

Which of the following cells have both activating and inhibitory receptors?

Correct AnswerverifiedShow Answer

Which of the following bests describes the effort to find a vaccine against HIV?

Correct AnswerverifiedShow Answer

If the following image depicts a virus in a weakened state, which of the choices would represent the type of vaccine that might be the safest to use?

Correct AnswerverifiedShow Answer

In a protein antigen, how many amino acids are necessary for the antigen to bind to a receptor on a T cell?

Correct AnswerverifiedShow Answer

Which portion of a T-cell receptor is furthest from the cell membrane of the T cell?

Correct AnswerverifiedShow Answer

Which of the following will be recognized as foreign by the activating receptors of macrophages?

Correct AnswerverifiedShow Answer

Plasma cells are derived from which type of cells?

Correct AnswerverifiedShow Answer

In HIV the protease and reverse transcriptase are enclosed by which of the following?

Correct AnswerverifiedShow Answer

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